Experimental Models

To replicate the complexity of tumor biology and explore its clinical relevance, we utilize diverse experimental models:

• In Vitro Models: These include murine and patient-derived  2D and 3D cell cultures such as primary cell lines, tumor spheres, and organoids, which closely mimic the heterogeneity and complexity of human tumors, offering insights into patient-specific tumor biology.
• Precision-Cut Organ Slices: Precision-cut organ slices from brain and lung tissues are used to study tumor colonization and microenvironmental interactions in a controlled ex vivo setting, bridging in vitro and in vivo studies.
• In Vivo Models: Mouse models are employed to study tumor growth, metastasis, and the dynamic interactions between tumor cells and their microenvironment within a living organism.

For more information, visit the research laboratory on a 3D Virtual Tour