Publikationen

Publikationen 2024

Brichkina A, Ems M, Suezov R, Singh R, Lutz V, Picard FSR, Nist A, Stiewe T, Graumann J, Daude M, Diederich WE, Finkernagel F, Chung HR, Bartsch DK, Roth K, Keber C, Denkert C, Huber M, Gress TM, Lauth M. DYRK1B blockade promotes tumoricidal macrophage activity in pancreatic cancer. Gut. 2024 Jun 4:gutjnl-2023-331854. doi: 10.1136/gutjnl-2023-331854. Epub ahead of print. PMID: 38834297.

Wächter S, Bartsch DK. Die Adrenalektomie verbessert bei Patienten mit leichter autonomer Kortisolsekretion die Kontrolle des Körpergewichts, des Blutzuckerspiegels und des Blutdrucks : Ergebnisse einer kontrollierten randomisierten Studie [In patients with mild autonomous cortisol secretion adrenalectomy improves the control of body weight, blood glucose levels and blood pressure : Results of a controlled randomized study]. Chirurgie (Heidelb). 2024 May 24. German. doi: 10.1007/s00104-024-02108-8. Epub ahead of print. PMID: 38789801.

Maurer E, Bartsch DK. Lokale Resektion von neuroendokrinen Tumoren des Dünndarms (SI-NEN) : Aktuelle Prinzipien [Local resection of small intestine neuroendocrine neoplasms (SI-NEN) : Current principles]. Chirurgie (Heidelb). 2024 May 21. German. doi: 10.1007/s00104-024-02102-0. Epub ahead of print. PMID: 38771340.

Maurer E, Bartsch DK. Surgical aspects related to hereditary pancreatic cancer. Fam Cancer. 2024 Apr 25. doi: 10.1007/s10689-024-00384-1. Epub ahead of print. PMID: 38662263.

Wächter S, Bartsch DK. Radiofrequenzablation benigner Schilddrüsenknoten: eine prospektive multizentrische nordamerikanische Studie [Radiofrequency ablation of benign thyroid nodules: A prospective, multi-institutional North American experience]. Chirurgie (Heidelb). 2024 May;95(5):406-407. German. doi: 10.1007/s00104-024-02074-1. Epub 2024 Apr 4. PMID: 38573323.

Partelli S, Fermi F, Fusai GK, Tamburrino D, Lykoudis P, Beghdadi N, Dokmak S, Wiese D, Landoni L, Reich F, Busch ORC, Napoli N, Jang JY, Kwon W, Armstrong T, Allen PJ, He J, Javed A, Sauvanet A, Bartsch DK, Salvia R, van Dijkum EJMN, Besselink MG, Boggi U, Kim SW, Wolfgang CL, Falconi M. ASO Visual Abstract: The Value of Textbook Outcome in Benchmarking Pancreatoduodenectomy for Nonfunctioning Pancreatic Neuroendocrine Tumors. Ann Surg Oncol. 2024 Jun;31(6):4123-4124. doi: 10.1245/s10434-024-15190-3. PMID: 38519785.

Mintziras I, Görg M, Wächter S, Manoharan J, Albers MB, Maurer E, Kanngiesser V, Jesinghaus M, Bartsch DK. Acinar content at pancreatic resection margin is significantly associated with clinically relevant pancreatic fistula after partial pancreatoduodenectomy. J Gastrointest Surg. 2024 Mar;28(3):252-258. doi: 10.1016/j.gassur.2023.12.030. Epub 2024 Jan 23. PMID: 38445917.

Manoharan J, Bartsch DK. Ist eine Zentralisierung der operativen Therapie neuroendokriner Tumoren des Dünndarms sinnvoll? [Is a centralization of surgical treatment for neuroendocrine tumors of the small intestine meaningful?]. Chirurgie (Heidelb). 2024 Apr;95(4):307-308. German. doi: 10.1007/s00104-024-02059-0. Epub 2024 Mar 5. PMID: 38441625.

Bartsch DK. Therapieindividualisierung in der endokrinen Chirurgie [Individualization of treatment in endocrine surgery]. Chirurgie (Heidelb). 2024 Mar;95(3):177-178. German. doi: 10.1007/s00104-023-02008-3. Epub 2024 Feb 20. PMID: 38376508.

Grass A, Kasajima A, Foersch S, Kriegsmann M, Brobeil A, Schmitt M, Wagner D, Poppinga J, Wiese D, Maurer E, Kirschbaum A, Muley T, Winter H, Rinke A, Gress TM, Kremer M, Evert M, Märkl B, Quaas A, Eckstein M, Tschurtschenthaler M, Klöppel G, Denkert C, Bartsch DK, Jesinghaus M. PITX2 as a Sensitive and Specific Marker of Midgut Neuroendocrine Tumors: Results from a Cohort of 1157 Primary Neuroendocrine Neoplasms. Mod Pathol. 2024 Apr;37(4):100442. doi: 10.1016/j.modpat.2024.100442. Epub 2024 Feb 1. PMID: 38309431.

Graf SD, Keber CU, Hattesohl A, Teply-Szymanski J, Hattesohl S, Guder M, Gercke N, Di Fazio P, Slater EP, Jesinghaus M, Denkert C, Bartsch DK, Lehman B. Mesenteric fibrosis in patients with small intestinal neuroendocrine tumors is associated with enrichment of alpha-smooth muscle actin-positive fibrosis and COMP-expressing stromal cells. J Neuroendocrinol. 2024 Feb;36(2):e13364. doi: 10.1111/jne.13364. Epub 2024 Jan 21. PMID: 38246597.

Brugger M, Lutz M, Müller-Nurasyid M, Lichtner P, Slater EP, Matthäi E, Bartsch DK, Strauch K. Joint Linkage and Association Analysis Using GENEHUNTER-MODSCORE with an Application to Familial Pancreatic Cancer. Hum Hered. 2024;89(1):8-31. doi: 10.1159/000535840. Epub 2024 Jan 10. PMID: 38198765.

Manoharan J, Albers MB, Bartsch DK. Individualisiertes Vorgehen bei MEN1-assoziierten duodenopankreatischen neuroendokrinen Neoplasien [Individualized approach for MEN1-associated duodenopancreatic neuroendocrine neoplasms]. Chirurgie (Heidelb). 2024 Mar;95(3):207-215. German. doi: 10.1007/s00104-023-01994-8. Epub 2024 Jan 5. PMID: 38180518.

Panidis D, Bartsch DK. Hemikolektomie rechts vs. Appendektomie bei Patienten mit Appendix-NEN zwischen 1–2 cm [Right hemicolectomy vs. appendectomy in patients with appendiceal NENs 1-2cm in size]. Chirurgie (Heidelb). 2024 Feb;95(2):157-158. German. doi: 10.1007/s00104-023-02026-1. Epub 2024 Jan 4. PMID: 38175201.

Wächter S, Bartsch DK, Maurer E. Personalisiertes Vorgehen beim anaplastischen Schilddrüsenkarzinom [Personalized approach to anaplastic thyroid carcinoma]. Chirurgie (Heidelb). 2024 Mar;95(3):192-199. German. doi: 10.1007/s00104-023-01993-9. Epub 2023 Nov 16. PMID: 37973622.

Publikationen 2023

Gimbel S, Bartsch DK. Verwendung der Near-Infrarot-Autofluoreszenz zur intraoperativen Identifikation von Nebenschilddrüsen beim primären Hyperparathyreoidismus – eine randomisierte Studie [Use of near-infrared autofluorescence for intraoperative identification of parathyroid glands in primary hyperparathyroidism-A randomized study]. Chirurgie (Heidelb). 2023 Nov;94(11):959-960. German. doi: 10.1007/s00104-023-01968-w. Epub 2023 Oct 2. PMID: 37782320.

Döring C, Peer K, Bankov K, Bollmann C, Ramaswamy A, Di Fazio P, Wild PJ, Bartsch DK. Whole-exome sequencing of calcitonin-producing pancreatic neuroendocrine neoplasms indicates a unique molecular signature. Front Oncol. 2023 Sep 12;13:1160921. doi: 10.3389/fonc.2023.1160921. PMID: 37771441; PMCID: PMC10522832.

Mintziras I, Wächter S, Manoharan J, Albers MB, Kanngiesser V, Maurer E, Bartsch DK. Serum amylase on postoperative day 1 is superior to serum lipase in predicting clinically relevant pancreatic fistula after partial pancreaticoduodenectomy. Langenbecks Arch Surg. 2023 Sep 16;408(1):359. doi: 10.1007/s00423-023-03090-1. PMID: 37714999.

Kirschbaum A, Jochens N, Stay D, Meyer C, Bartsch DK. Continuous intraoperative neuromonitoring of the recurrent laryngeal nerve during lung operations. J Thorac Dis. 2023 Aug 31;15(8):4198-4206. doi: 10.21037/jtd-22-1515. Epub 2023 Jul 13. PMID: 37691667; PMCID: PMC10482653.

Maurer E, Bartsch DK. 11C-Metomidate-PET/CT versus selektive Nebennierenvenenblutentnahme zur Vorhersage des Operationserfolgs beim primären Hyperaldosteronismus : Ergebnisse der prospektiven MATCH-Studie [11C-metomidate PET-CT vs. selective adrenal vein sampling for prediction of surgical success in primary aldosteronism : Results of the prospective MATCH study]. Chirurgie (Heidelb). 2023 Oct;94(10):877-878. German. doi: 10.1007/s00104-023-01957-z. Epub 2023 Sep 8. PMID: 37682281.

Litmeyer AS, Konukiewitz B, Kasajima A, Foersch S, Schicktanz F, Schmitt M, Kellers F, Grass A, Jank P, Lehman B, Gress TM, Rinke A, Bartsch DK, Denkert C, Weichert W, Klöppel G, Jesinghaus M. High expression of insulinoma-associated protein 1 (INSM1) distinguishes colorectal mixed and pure neuroendocrine carcinomas from conventional adenocarcinomas with diffuse expression of synaptophysin. J Pathol Clin Res. 2023 Nov;9(6):498-509. doi: 10.1002/cjp2.339. Epub 2023 Aug 22. PMID: 37608427; PMCID: PMC10556265.

Manoharan J, Albers M, Bartsch DK. Indikation und operative Verfahren bei MEN1-assoziierten duodenopankreatischen neuroendokrinen Neoplasien [Indication and Surgical Procedures for MEN1-associated Duodenopancreatic Neuroendocrine Neoplasms]. Zentralbl Chir. 2023 Dec;148(6):483-491. German. doi: 10.1055/a-2103-3525. Epub 2023 Aug 21. PMID: 37604166.

Hofland J, Falconi M, Christ E, Castaño JP, Faggiano A, Lamarca A, Perren A, Petrucci S, Prasad V, Ruszniewski P, Thirlwell C, Vullierme MP, Welin S, Bartsch DK. European Neuroendocrine Tumor Society 2023 guidance paper for functioning pancreatic neuroendocrine tumour syndromes. J Neuroendocrinol. 2023 Aug;35(8):e13318. doi: 10.1111/jne.13318. Epub 2023 Aug 14. PMID: 37578384.

Wächter S, Bartsch DK. Sofortige vs. sekundäre Operation beim papillären Mikrokarzinom der Schilddrüse [Immediate vs. secondary surgery for papillary microcarcinoma of the thyroid gland]. Chirurgie (Heidelb). 2023 Sep;94(9):804-805. German. doi: 10.1007/s00104-023-01944-4. Epub 2023 Aug 8. PMID: 37552288.

Wiese D, Bartsch DK. Prognostische und operationstechnische Faktoren für ein Rezidiv nach Resektion eines sporadischen Gastrinoms [Prognostic and surgical technique factors for recurrence after resection of a sporadic gastrinoma]. Chirurgie (Heidelb). 2023 Aug;94(8):731-732. German. doi: 10.1007/s00104-023-01928-4. Epub 2023 Jun 30. PMID: 37389640.

Wiese D, Humburg FG, Kann PH, Rinke A, Luster M, Mahnken A, Bartsch DK. Changes in diagnosis and operative treatment of insulinoma over two decades. Langenbecks Arch Surg. 2023 Jun 29;408(1):255. doi: 10.1007/s00423-023-02974-6. PMID: 37386194; PMCID: PMC10310606.

Bartsch DK. Chirurgie des Hyperparathyreoidismus [Surgery of hyperparathyroidism]. Chirurgie (Heidelb). 2023 Jul;94(7):571-572. German. doi: 10.1007/s00104-023-01856-3. Epub 2023 Jun 29. PMID: 37382690.

Wächter S, Roth S, Gercke N, Schötz U, Dikomey E, Engenhart-Cabillic R, Maurer E, Bartsch DK, Di Fazio P. Anti-Proliferative Effect of Radiotherapy and Implication of Immunotherapy in Anaplastic Thyroid Cancer Cells. Life (Basel). 2023 Jun 15;13(6):1397. doi: 10.3390/life13061397. PMID: 37374179; PMCID: PMC10301015.

Wiese D, Bartsch DK. Ist eine endosonographisch gesteuerte Radiofrequenzablation beim Insulinom eine sinnvolle Alternative zur Operation? [Is endosonography-guided radiofrequency ablation of insulinoma a reasonable alternative to surgery?]. Chirurgie (Heidelb). 2023 Jun;94(6):550-551. German. doi: 10.1007/s00104-023-01883-0. Epub 2023 May 4. PMID: 37140658.

Maurer E, Bartsch DK. Ambulante Nebenschilddrüsenoperationen im deutschen System – Möglich und sinnvoll? [Outpatient parathyroid gland operations in the German system-Feasible and useful?]. Chirurgie (Heidelb). 2023 Jul;94(7):580-585. German. doi: 10.1007/s00104-023-01846-5. Epub 2023 Mar 10. PMID: 36897344.

Höhn P, Runde F, Luu AM, Fahlbusch T, Fein D, Klinger C, Uhl W, Belyaev O; members of StuDoQ|Pancreas registry of the German Society for General and Visceral Surgery (DGAV); Keck T, Werner J, Nüssler N, Bartsch DK, Germer CT, Friess H, Mönch C, Oldhafer KJ, Kalff JC. Applicability of the surgical risk calculator by the American College of Surgeons in the setting of German patients undergoing complete pancreatectomy: multicentre study using data from the StuDoQ|Pancreas registry. BJS Open. 2023 Mar 7;7(2):zrac164. doi: 10.1093/bjsopen/zrac164. PMID: 36882081; PMCID: PMC9991503.

Maurer E, Bartsch DK. Langzeitergebnisse nach parenchymsparender vs. onkologischer Resektion bei nichtfunktionellen pankreatischen neuroendokrinen Neoplasien < 3 cm [Long-term results after parenchyma-sparing vs. oncologic resection of nonfunctional pancreatic neuroendocrine neoplasms < 3 cm]. Chirurgie (Heidelb). 2023 Apr;94(4):365-366. German. doi: 10.1007/s00104-023-01843-8. Epub 2023 Feb 27. PMID: 36849588.

Matrood S, Melms LE, Bartsch DK, Di Fazio P. The Expression of Autophagy-Associated Genes Represents a Valid Footprint for Aggressive Pancreatic Neuroendocrine Neoplasms. Int J Mol Sci. 2023 Feb 11;24(4):3636. doi: 10.3390/ijms24043636. PMID: 36835048; PMCID: PMC9966877.

Wächter S, Knauff F, Roth S, Keber C, Holzer K, Manoharan J, Maurer E, Bartsch DK, Di Fazio P. Synergic Induction of Autophagic Cell Death in Anaplastic Thyroid Carcinoma. Cancer Invest. 2023 Apr;41(4):405-421. doi: 10.1080/07357907.2023.2183027. Epub 2023 Mar 1. PMID: 36811581.

Wächter S, Bartsch DK. Effizienz und Sicherheit der Radiofrequenzablation benigner Schilddrüsenknoten [Efficiency and safety of radiofrequency ablation of benign thyroid nodules]. Chirurgie (Heidelb). 2023 Mar;94(3):268-269. German. doi: 10.1007/s00104-023-01831-y. Epub 2023 Feb 14. PMID: 36786811.

Picard FSR, Lutz V, Brichkina A, Neuhaus F, Ruckenbrod T, Hupfer A, Raifer H, Klein M, Bopp T, Pfefferle PI, Savai R, Prinz I, Waisman A, Moos S, Chang HD, Heinrich S, Bartsch DK, Buchholz M, Singh S, Tu M, Klein L, Bauer C, Liefke R, Burchert A, Chung HR, Mayer P, Gress TM, Lauth M, Gaida M, Huber M. IL-17A-producing CD8+ T cells promote PDAC via induction of inflammatory cancer-associated fibroblasts. Gut. 2023 Aug;72(8):1510-1522. doi: 10.1136/gutjnl-2022-327855. Epub 2023 Feb 9. PMID: 36759154; PMCID: PMC10359545.

Lehman B, Matthäi E, Gercke N, Denzer UW, Figiel J, Hess T, Slater EP, Bartsch DK. Characteristics of familial pancreatic cancer families with additional colorectal carcinoma. Fam Cancer. 2023 Jul;22(3):323-330. doi: 10.1007/s10689-023-00328-1. Epub 2023 Jan 31. PMID: 36717525; PMCID: PMC10276072.

Ha CSR, Müller-Nurasyid M, Petrera A, Hauck SM, Marini F, Bartsch DK, Slater EP, Strauch K. Proteomics biomarker discovery for individualized prevention of familial pancreatic cancer using statistical learning. PLoS One. 2023 Jan 26;18(1):e0280399. doi: 10.1371/journal.pone.0280399. PMID: 36701413; PMCID: PMC9879447.

Maurer E, Eilsberger F, Wächter S, Riera Knorrenschild J, Pehl A, Holzer K, Neubauer A, Luster M, Bartsch DK. Mutation-based, short-term "neoadjuvant" treatment allows resectability in stage IVB and C anaplastic thyroid cancer. Eur Arch Otorhinolaryngol. 2023 Mar;280(3):1509-1518. doi: 10.1007/s00405-023-07827-y. Epub 2023 Jan 13. PMID: 36637521; PMCID: PMC9899736.

Bartsch DK, Maurer E. Ist die Radiojodtherapie nach Thyreoidektomie beim „niedrig-Risiko“-differenzierten Schilddrüsenkarzinom erforderlich? : Ergebnisse der französischen prospektiv randomisierten Multicenterstudie ESTIMABL2 [Is radioiodine treatment necessary after thyroidectomy for "low-risk" differentiated thyroid cancer? : Results of the French prospective randomized multicenter ESTIMBL2 study]. Chirurgie (Heidelb). 2023 Feb;94(2):168-169. German. doi: 10.1007/s00104-022-01797-3. Epub 2023 Jan 5. PMID: 36604319.

Stark M, Nicolai M, Tatura M, Keber CU, Kaufmann A, Chung HR, Slater EP, Heeschen C, Lawlor RT, Scarpa A, Bartsch DK, Gress TM, Bauer S, Buchholz M. Dissecting the role of toll-like receptor 7 in pancreatic cancer. Cancer Med. 2023 Apr;12(7):8542-8556. doi: 10.1002/cam4.5606. Epub 2023 Jan 5. PMID: 36602302; PMCID: PMC10134280.

Seufferlein T, Uhl W, Kornmann M, Algül H, Friess H, König A, Ghadimi M, Gallmeier E, Bartsch DK, Lutz MP, Metzger R, Wille K, Gerdes B, Schimanski CC, Graupe F, Kunzmann V, Klein I, Geissler M, Staib L, Waldschmidt D, Bruns C, Wittel U, Fichtner-Feigl S, Daum S, Hinke A, Blome L, Tannapfel A, Kleger A, Berger AW, Kestler AMR, Schuhbaur JS, Perkhofer L, Tempero M, Reinacher-Schick AC, Ettrich TJ. Perioperative or only adjuvant gemcitabine plus nab-paclitaxel for resectable pancreatic cancer (NEONAX)-a randomized phase II trial of the AIO pancreatic cancer group. Ann Oncol. 2023 Jan;34(1):91-100. doi: 10.1016/j.annonc.2022.09.161. Epub 2022 Oct 7. PMID: 36209981.

Klabunde B, Wesener A, Bertrams W, Beinborn I, Paczia N, Surmann K, Blankenburg S, Wilhelm J, Serrania J, Knoops K, Elsayed EM, Laakmann K, Jung AL, Kirschbaum A, Hammerschmidt S, Alshaar B, Gisch N, Abu Mraheil M, Becker A,
Völker U, Vollmeister E, Benedikter BJ, Schmeck B. NAD - metabolism is a key modulator of bacterial respiratory epithelial infections. Nat Commun. 2023 Oct 2;14(1):5818. doi: 10.1038/s41467-023-41372-w. PMID: 37783679; PMCID:
PMC10545792.

Irqsusi M, Ghazy T, Vogt S, Mirow N, Kirschbaum A. T4 Lung Carcinoma with Infiltration of the Thoracic Aorta: Indication and Surgical Procedure. Cancers (Basel). 2023 Oct 4;15(19):4847. doi: 10.3390/cancers15194847. PMID: 37835540;
PMCID: PMC10572069.

Zaraca F, Kirschbaum A, Pipitone MD, Bertolaccini L; PATCHES study group. Prospective randomized study on the efficacy of three-dimensional reconstructions of bronchovascular structures on preoperative chest CT scan in patients who are candidates for pulmonary segmentectomy surgery: the PATCHES (Prospective rAndomized sTudy efficaCy of tHree-dimensional rEconstructions Segmentecomy) study protocol. Trials. 2023 Sep 16;24(1):594. doi: 10.1186/s13063-023-07600-w. Erratum in: Trials. 2023 Oct 3;24(1):629. PMID: 37717001; PMCID: PMC10504737.

Irqsusi M, Dielmann K, Talipov I, Rastan A, Bartsch D, Kirschbaum A. Reduction of volume loss after left atrial injury by balloon occlusion-an experimental study. J Thorac Dis. 2023 Nov 30;15(11):6040-6046. doi: 10.21037/jtd-23-247. Epub 2023 Nov 6. PMID: 38090307; PMCID: PMC10713283.

Hüppe T, Kreuer S, Wulf H, Freitag D, Seidel M, Teucke T, Maurer F, Kirschbaum A, Koch T, Langer F, Volk T, Feldmann C. Quantification of exhaled propofol is not feasible during single-lung ventilation using double-lumen tubes: A multicenter prospective observational trial. Acta Anaesthesiol Scand. 2023 Apr;67(4):455-461. doi: 10.1111/aas.14201. Epub 2023 Jan 27. PMID: 36644966.

Zaraca F, Kirschbaum A, Pipitone MD, Bertolaccini L; PATCHES study group. Correction: Prospective randomized study on the efficacy of three-dimensional reconstructions of bronchovascular structures on preoperative chest CT scan in
patients who are candidates for pulmonary segmentectomy surgery: the PATCHES (Prospective rAndomized sTudy efficaCy of tHree-dimensional rEconstructions Segmentecomy) study protocol. Trials. 2023 Oct 3;24(1):629. doi: 10.1186/s13063-023-07671-9. Erratum for: Trials. 2023 Sep 16;24(1):594. PMID: 37789368; PMCID: PMC10546708.