Team

Publikationen

Richter K, Ogiemwonyi-Schaefer R, Wilker S, Chaveiro AI, Agné A, Hecker M, Reichert M, Amati AL, Schlüter KD, Manzini I, Schmalzing G, McIntosh JM, Padberg W, Grau V, Hecker A. 
Amyloid Beta Peptide (Aβ1-42) Reverses the Cholinergic Control of Monocytic IL-1β Release.
J Clin Med. 2020 Sep 7;9(9):E2887.
Abstract

Agné A, Richter K, Tumpara S, Sauer AL, Beckert F, Wrenger S, Zakrzewicz A, Hecker A, Markmann M, Koch C, Zajonz T, Sander M, Böning A, Padberg W, Janciauskiene S, Grau V.
Does heart surgery change the capacity of α1-antitrypsin to inhibit the ATP-induced release of monocytic interleukin-1β? A preliminary study.
Int Immunopharmacol. 2020 Feb 12;81:106297.
Abstract

Zakrzewicz A, Richter K, Zakrzewicz D, Siebers K, Damm J, Agné A, Hecker A, McIntosh JM, Chamulitrat W, Krasteva-Christ G, Manzini I, Tikkanen R, Padberg W, Janciauskiene S, Grau V.
SLPI Inhibits ATP-Mediated Maturation of IL-1β in Human Monocytic Leukocytes: A Novel Function of an Old Player.
Front Immunol. 2019 Apr 4;10:664. doi: 10.3389/fimmu.2019.00664. eCollection 2019.
Abstract

Grau V, Richter K, Hone AJ, McIntosh JM.
Conopeptides [V11L;V16D]ArIB and RgIA4: Powerful Tools for the Identification of Novel Nicotinic Acetylcholine Receptors in Monocytes.
Front Pharmacol. 2019 Jan 7;9:1499.  eCollection 2018.
Abstract

Richter K, Sagawe S, Hecker A, Küllmar M, Askevold I, Damm J, Heldmann S, Pöhlmann M, Ruhrmann S, Sander M, Schlüter KD, Wilker S, König IR Kummer W, Padberg W, Hone AJ, McIntosh JM, Zakrzewicz AT, Koch C, Grau V.
C-Reactive Protein Stimulates Nicotinic Acetylcholine Receptors to Control ATP-Mediated Monocytic Inflammasome Activation.
Front Immunol. 2018 Jul 30;9:1604.
Abstract


Richter K, Koch C, Perniss A, Wolf PM, Schweda EKH, Wichmann S, Wilker S, Magel I, Sander M, McIntosh JM, Padberg W, Grau V.
Phosphocholine-Modified Lipooligosaccharides of Haemophilus influenzae Inhibit ATP-Induced IL-1β Release by Pulmonary Epithelial Cells.
Molecules. 2018 Aug 8;23(8). pii: E1979.
Abstract

Siebers K, Fink B, Zakrzewicz A, Agné A, Richter K, Konzok S, Hecker A, Zukunft S, Küllmar M, Klein J, McIntosh JM, Timm T, Sewald K, Padberg W, Aggarwal N, Chamulitrat W, Santoso S, Xia W., Janciauskiene S, Grau V.
Alpha-1 Antitrypsin Inhibits ATP-Mediated Release of Interleukin-1β via CD36 and Nicotinic Acetylcholine Receptors.
Front Immunol. 2018 Apr 25;9:877.
Abstract


Hiller SD, Heldmann S, Richter K, Jurastow I, Küllmar M, Hecker A, Wilker S, Fuchs-Moll G, Manzini I, Schmalzing G, Kummer W, Padberg W, McIntosh JM, Damm J, Zakrzewicz A, Grau V.
β-Nicotinamide Adenine Dinucleotide (β-NAD) Inhibits ATP-Dependent IL-1β Release from Human Monocytic Cells.
Int J Mol Sci. 2018 Apr 10;19(4). pii: E1126.
Abstract

Marchetti C, Swartzwelter B, Gamboni F, Neff CP, Richter K, Azam T, Carta S, Tengesdal I, Nemkov T, D'Alessandro A, Henry C, Jones GS, Goodrich SA, St Laurent JP, Jones TM, Scribner CL, Barrow RB, Altman RD, Skouras DB, Gattorno M, Grau V, Janciauskiene S, Rubartelli A, Joosten LAB, Dinarello CA.
OLT1177, a β-sulfonyl nitrile compound, safe in humans, inhibits the NLRP3 inflammasome and reverses the metabolic cost of inflammation.
Proc Natl Acad Sci U S A. 2018 Feb 13;115(7):E1530-E1539.
Abstract

Backhaus S, Zakrzewicz A, Richter K, Damm J, Wilker S, Fuchs-Moll G, Küllmar M, Hecker A, Manzini I, Ruppert C, McIntosh JM, Padberg W, Grau V.
Surfactant inhibits ATP-induced release of interleukin-1β via nicotinic acetylcholine receptors.
J Lipid Res. 2017 Jun;58(6):1055-1066.
Abstract


Richter K, Mathes V, Fronius M, Althaus M, Hecker A, Krasteva-Christ G, Padberg W, Hone AJ, McIntosh JM, Zakrzewicz A, Grau V.
Phosphocholine - an agonist of metabotropic but not of ionotropic functions of α9-containing nicotinic acetylcholine receptors.
Sci Rep. 2016 Jun 28;6:28660. doi: 10.1038/srep28660.
Abstract


Hecker A, Küllmar M, Wilker S, Richter K, Zakrzewicz A, Atanasova S, Mathes V, Timm T, Lerner S, Klein J, Kaufmann A, Bauer S, Padberg W, Kummer W, Janciauskiene S, Fronius M, Schweda EK, Lochnit G, Grau V.
Phosphocholine-Modified Macromolecules and Canonical Nicotinic Agonists Inhibit ATP-Induced IL-1β Release.
J Immunol. 2015 Sep 1;195(5):2325-34.
Abstract